Isoprostanes: Are They More Than Physiopathological Biomarkers of Lipid Peroxidation?
نویسندگان
چکیده
منابع مشابه
Isoprostanes: are they more than physiopathological biomarkers of lipid peroxidation?
Biomarkers of Lipid Peroxidation? To the Editor: Isoprostanes are currently used as biomarkers of lipid peroxidation in humans.1 Minuz et al2 recently showed that urinary levels of 15-F2t-IsoP were increased in hypertensive patients suffering from renovascular disease, confirming the experimental data showing that renovascular hypertension and activation of the renin-angiotensin system in gener...
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Increased lipid peroxidation has been identified as a key mechanism for the development of atherosclerosis and inflammatory vascular damage. Determination of plasma concentration and urinary excretion of some F(2)-isoprostanes (by immunometric assays or by mass-spectrometry), has been demonstrated to be a reliable approach to the assessment of lipid peroxidation, and therefore of oxidative stre...
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Isoprostanes (IsoPs) are key biomarkers for investigating the role of free radical generation in the pathogenesis of human disorders. To solve IsoPs-related problems with regard to isoprostanes, analytical tools are required. This paper reviews the problems and trends in this field focusing on the methodology for assaying biomarkers in exhaled breath condensate (EBC) samples. A large amount of ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2003
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.0000077640.74263.82